Stem cells in the treatment of Autism
Cord blood stem cells have shown good results in the treatment of Autism. Stem cells possess unique properties that can help in managing and alleviating the challenges of Autism.
Cord blood stem cells have regenerative capabilities..
Stem cells are powerful tools in medical treatment due to their ability to develop into various specialized cell types. This potential makes them promising for treating many health conditions, including autism spectrum disorder (ASD).
ASD is a complex neurodevelopmental disorder characterized by social communication challenges, repetitive behaviours, and restricted interests. While the exact causes of ASD are not fully understood, research is exploring the potential of stem cell treatment to alleviate some of its symptoms.
Stem cells can transform into different cell types, playing a crucial role in the body's growth, repair, and maintenance. They can replace damaged or dysfunctional cells, offering hope for tissue regeneration. There are different types of stem cells, including embryonic stem cells, adult stem cells, and induced pluripotent stem cells (iPSCs), each with unique capabilities.
For autism treatment, stem cells may help by modulating immune responses and reducing inflammation, which are factors in the neurodevelopmental processes of ASD. They might also aid in neural repair, potentially restoring disrupted neural networks in individuals with ASD. Some studies suggest that stem cells could release neuroprotective and anti-inflammatory factors, creating a more favourable environment for neural growth and connectivity.
One of the primary benefits of cord blood stem cells is their ability to modulate the immune system. Stem cells are a powerful regenerative medicine due to their ability to transform into various specialized cell types, which play a crucial role in the body's growth, repair, rejuvenation and maintenance allowing them to replace damaged or dysfunctional cells, offering hope for tissue regeneration in many health conditions, incl. Exiting Positive Results from studies in Autism (ASD), Joint Repair, Cancer and many auto-immune diseases.
Patients who receive cord blood stem cell therapy for Autism report significant improvements.
We primarily use umbilical cord blood and cord tissue-derived stem cells, which are highly effective and do not require a blood match for transplantation. These cells are thoroughly screened to ensure their safety and efficacy.
The stem cell procedure itself is minimally invasive and performed in a hospital setting (address below). It is typically a short procedure, and while some slight discomfort may be experienced, it is generally not painful.
All cord blood stem cells are derived from healthy donors.
Further Information regarding the stem cells used:
How cord blood stem cells are analysed to determine if they come from donors who have not received any COVID-19 vaccines involves a few steps:
Protocol for the Analysis of Cord Blood Stem Cells and process:
1st stage: Donor Screening and Documentation: The first method used is to rely on thorough donor screening and documentation. Donors are asked about their vaccination status, and this information is recorded and verified through medical records.
2nd stage: is Flow Cytometry: This technique is used to analyse specific markers on the surface of stem cells. While flow cytometry is typically used to assess cell viability and count specific cell types, it's adapted to detect markers or changes associated with Covid 19 variant vaccinations.
3rd stage: Genetic and Epigenetic Analysis: Advanced epigenetic analysis helps them reveal changes in gene expression or other markers that also indicates a history of COVID-19 vaccination.
4th stage: Serological Testing: Testing for the presence of antibodies specific to COVID-19 vaccines in the donor's blood which is a strong indicator whether they have been vaccinated against COVID-19.
5th stage: Cell Culture and Functional Assays: Culturing the stem cells and performing functional assays reveal differences in cell behaviour or response to stimuli that are linked to COVID-19 vaccination status
Other analysis to include:
· Sterility Testing: Cord blood samples are tested for microbial contamination to ensure they are free from harmful bacteria, viruses, and fungi. This is crucial to prevent infections in recipients.
· Infectious Disease Screening: The blood is tested for all infectious diseases such as HIV, hepatitis, and syphilis to ensure that the cells are safe for administration.
· Genetic Testing: While cord blood stem cells do not require a perfect blood match, genetic testing is still performed to ensure they are suitable for administration and to identify any potential genetic disorders.
· Quality Control: Throughout the processing and storage of cord blood, strict quality control measures are in place to maintain the integrity and viability of the stem cells. This includes monitoring the cells during cryopreservation (freezing) and ensuring proper handling and storage conditions.
· Volume Reduction: The cord blood is processed to remove excess red blood cells and plasma, leaving behind a concentrated sample of stem cells.
Administration of Stem Cells for Autism
The administration of stem cells typically takes about 2 to 3 hours. When used to treat autism, stem cell therapy can prevent the progression of the condition and improve the patient's current state. Benefits observed after treatment include cognitive development, increased learning capacity, better information retention, improved environmental compliance, enhanced digestive function, and a stronger immune system.
• Stem cells can turn into nerve, brain, and muscle cells, making them useful for treating autism. The transplanted stem cells do not carry the disorder, so they replace damaged cells and may slow, stop, or reverse the disease's progression.
• Treatment protocols are tailored to each patient's condition, with different protocols for each individual.
• Stem cell therapy has shown very positive results in autism patients, preventing disease progression in 85% of cases and helping to resolve existing conditions. The type of stem cells used is CB-MNC.
• Patients respond at different rates. The amount of stem cells required depends on where the patient is on the spectrum. Stem cells multiply, so full effects are seen after 3 months.
• For example, the first administration might involve 35 million stem cells, with each vial containing 7 million stem cells. Five vials are administered via IV, and the cost per patient is around $2500. ($6000 for a 3 session booking)
A second session of stem cells is often recommended 3 months later.