Stem cells in the treatment of Autism
Cord blood stem cells have shown good results in the treatment of Autism. Stem cells possess unique properties that can help in managing and alleviating the challenges of Autism.
Cord blood stem cells have regenerative capabilities..
Stem cells are powerful tools in medical treatment due to their ability to develop into various specialized cell types. This potential makes them promising for treating many health conditions, including autism spectrum disorder (ASD).
ASD is a complex neurodevelopmental disorder characterized by social communication challenges, repetitive behaviours, and restricted interests. While the exact causes of ASD are not fully understood, research is exploring the potential of stem cell treatment to alleviate some of its symptoms.
Stem cells can transform into different cell types, playing a crucial role in the body's growth, repair, and maintenance. They can replace damaged or dysfunctional cells, offering hope for tissue regeneration. There are different types of stem cells, including embryonic stem cells, adult stem cells, and induced pluripotent stem cells (iPSCs), each with unique capabilities.
For autism treatment, stem cells may help by modulating immune responses and reducing inflammation, which are factors in the neurodevelopmental processes of ASD. They might also aid in neural repair, potentially restoring disrupted neural networks in individuals with ASD. Some studies suggest that stem cells could release neuroprotective and anti-inflammatory factors, creating a more favourable environment for neural growth and connectivity.
One of the primary benefits of cord blood stem cells is their ability to modulate the immune system. Stem cells are a powerful regenerative medicine due to their ability to transform into various specialized cell types, which play a crucial role in the body's growth, repair, rejuvenation and maintenance allowing them to replace damaged or dysfunctional cells, offering hope for tissue regeneration in many health conditions, incl. Exiting Positive Results from studies in Autism (ASD), Joint Repair, Cancer and many auto-immune diseases.
Patients who receive cord blood stem cell therapy for Autism report significant improvements.
We primarily use umbilical cord blood and cord tissue-derived stem cells, which are highly effective and do not require a blood match for transplantation. These cells are thoroughly screened to ensure their safety and efficacy.
The stem cell procedure itself is minimally invasive and performed in a hospital setting (address below). It is typically a short procedure, and while some slight discomfort may be experienced, it is generally not painful.
All cord blood stem cells are derived from healthy donors.
Further Information regarding the stem cells used:
How cord blood stem cells are analysed to determine if they come from donors who have not received any COVID-19 vaccines involves a few steps:
Protocol for the Analysis of Cord Blood Stem Cells and process:
1st stage: Donor Screening and Documentation: The first method used is to rely on thorough donor screening and documentation. Donors are asked about their vaccination status, and this information is recorded and verified through medical records.
2nd stage: is Flow Cytometry: This technique is used to analyse specific markers on the surface of stem cells. While flow cytometry is typically used to assess cell viability and count specific cell types, it's adapted to detect markers or changes associated with Covid 19 variant vaccinations.
3rd stage: Genetic and Epigenetic Analysis: Advanced epigenetic analysis helps them reveal changes in gene expression or other markers that also indicates a history of COVID-19 vaccination.
4th stage: Serological Testing: Testing for the presence of antibodies specific to COVID-19 vaccines in the donor's blood which is a strong indicator whether they have been vaccinated against COVID-19.
5th stage: Cell Culture and Functional Assays: Culturing the stem cells and performing functional assays reveal differences in cell behaviour or response to stimuli that are linked to COVID-19 vaccination status
Other analysis to include:
· Sterility Testing: Cord blood samples are tested for microbial contamination to ensure they are free from harmful bacteria, viruses, and fungi. This is crucial to prevent infections in recipients.
· Infectious Disease Screening: The blood is tested for all infectious diseases such as HIV, hepatitis, and syphilis to ensure that the cells are safe for administration.
· Genetic Testing: While cord blood stem cells do not require a perfect blood match, genetic testing is still performed to ensure they are suitable for administration and to identify any potential genetic disorders.
· Quality Control: Throughout the processing and storage of cord blood, strict quality control measures are in place to maintain the integrity and viability of the stem cells. This includes monitoring the cells during cryopreservation (freezing) and ensuring proper handling and storage conditions.
· Volume Reduction: The cord blood is processed to remove excess red blood cells and plasma, leaving behind a concentrated sample of stem cells.
Administración de células madre
La administración de células madre suele tardar entre 2 y 3 horas. Cuando se utiliza para tratar el autismo, la terapia con células madre puede prevenir la progresión de la enfermedad y mejorar el estado actual del paciente. Los beneficios observados después del tratamiento incluyen desarrollo cognitivo, aumento de la capacidad de aprendizaje, mejor retención de información, mejor adaptación al entorno, mejor función digestiva y un sistema inmunológico más fuerte.
• Las células madre pueden convertirse en células nerviosas, cerebrales y musculares, lo que las hace útiles para tratar el autismo. Las células madre trasplantadas no transmiten la enfermedad, por lo que reemplazan a las células dañadas y pueden ralentizar, detener o revertir la progresión de la enfermedad.
• Los protocolos de tratamiento se adaptan a la condición de cada paciente, con protocolos diferentes para cada individuo.
• La terapia con células madre ha demostrado resultados muy positivos en pacientes con autismo, previniendo la progresión de la enfermedad en el 85% de los casos y ayudando a resolver las afecciones existentes. El tipo de células madre utilizadas son las CB-MNC.
• Los pacientes responden a distintos ritmos. La cantidad de células madre necesarias depende de la etapa del espectro en la que se encuentre el paciente. Las células madre se multiplican, por lo que los efectos completos se observan después de 3 meses.
• Por ejemplo, la primera administración podría implicar 35 millones de células madre, y cada frasco contendría 7 millones de células madre. Se administran cinco frascos por vía intravenosa y el costo por paciente es de aproximadamente 2000 dólares.
Generalmente se recomienda una segunda sesión de células madre 3 meses después.